Los Angeles and San Francisco were the most expensive U.S. cities for the construction of general hospitals in the fourth quarter of 2021, a recent Statista report revealed.

Top 12 Cities Include Los Angeles Costs at Over $772 Per Square Foot, San Francisco is $707+
Building costs vary based on such factors as site conditions, climatic conditions and market conditions.
Below are the dozen most expensive cities in the U.S. for the construction of general hospitals and the average cost per square foot. A tie at No. 6 results in a numerical listing of 11:
1. Los Angeles: $772.5 per square foot
2. San Francisco: $707.5 per square foot
3. New York: $700 per square foot
4. Honolulu: $637.5 per square foot
5. Washington, D.C.: $632.5 per square foot
6. Chicago: $550 per square foot (tie)

6. Boston: $550 per square foot (tie)
7. Portland: $542.5 per square foot
8. Seattle: $540 per square foot
9. Denver: $520 per square foot
10. Phoenix: $502.5 per square foot
11. Las Vegas: $437.5 per square foot
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